Drinking Wines

Interest in wine?s health benefits in the last two decades may have been sparked by a desire to establish a reason for the so called ?French Paradox?. There is a where a lower incidence of heart disease is found in the French. The French have a diet rich in fat and it is rational to think this antagonistic diet would be incompatible with good health. The French are known to eat more beef, cheese and butter than their European neighbors. Several researchers concluded that along with their rich fatty foods they also have a significant intake of red wine when compared to other Europeans and even Westerners. Thus the door was open for many researchers to study the health effects of wine (especially red wine) as a possible solution to this quandary. There is research supported information that moderate red wine consumption (that is one glass for women and one to two for men) can protect you against heart disease, hypertension and cancer. It also has been shown to have a positive effect on cholesterol levels. Of course moderation is key here. This is certainly not an example of where a little is good a whole lot is better. Therefore, the medical community is very cautious to recommend routine use of red wine for obvious reasons.

Some studies in women regarding the consumption of alcohol and risk of breast cancer found an increase of this type of cancer in women who consume at least one drink daily. According to a report by the American Cancer Society in 2004 there was an increase of 30% in the death rate from breast cancer in women who would drink alcohol daily. This confounding information aside consumption of one or two drinks per day is associated with a reduction in risk of approximately 30 to 50 percent in coronary heart disease. Heart disease being the overwhelming number one killer of woman annually makes it the major target. So wine consumption has an overall positive effect on death rates in the female population.

The compounds responsible for the protective powers of wine are a class of compounds called antioxidants. Red wines contain several antioxidants the key isolate being the polyphenol compound called trans-Resveratrol or Res for short. Res is found in other fruit besides grapes including mulberries, raspberries and muscadine grapes (indigenous to the Americas). And in this particular grape Res is reported to be seven times as concentrated. Resveratrol is also encountered in peanuts and other nuts. Researchers at University of North Carolina-Chapel Hill and the University of Illinois found that Res has both anti-inflammatory and anti-cancer properties. A paper published by the UNC researchers in 2000 in the journal Cancer Research reports that Res inhibits the activity of a protein called NF-kappa B which attaches to DNA inside human cells. This protein acts like a switch turning certain genes on and off. Cancer cells propagate and continue to survive by means of NF-kappa B and thus under controlled settings researcher introduce Res which turns off this protein and thus causes the death (apoptosis) of cancer cells.

In 1992 Harvard Medical School researchers included moderate alcohol consumption as one of eight ways to reduce coronary heart disease risk. The cardioprotective effect is attributed to the antioxidants found in wine grape skins and seeds. These antioxidants (flavonoids) are found in higher concentration in red as opposed to white wine. As part of the red wine making process grape skins, stems and seeds are kept in contact with the juice for a long period of time imparting not only the ?red? color but also these health-benefiting flavonoids. It should also be noted that certain flavonoids found in oak wood are conveyed, as many red wine spends much time ?aging? in oak barrels.

Coronary heart disease reduction by Res and other antioxidant flavonoids occur in part due to a reduction in the production of low-density lipoprotein cholesterol (LDL-C) and the increase of the good high density lipoprotein cholesterol (HDL-C). Additionally these agents reduce blood-clotting factors limiting thrombus from causing ?clots? in the coronary arteries. Some of these properties may be attributed to the fact that Res has mild estrogenic properties and estrogens as a class of hormones seem to be cardioprotective.

Still another study indicated that Resveratrol aided in the formation of nerve cells. There are those experts that believe this may be helpful in the treatment of neurological diseases such as Alzheimer?s and Parkinson?s in the near future. There is even one study out there claiming that daily moderate wine consumption will result in weight loss.

Not all wines are created equally. Studies from the University of California at Davis conducted studies on several varietals. They determined that higher concentrations of flavonoids are present in Cabernet Sauvignon, followed by Petit Syrah and Pinot Noir grapes. Merlot and Red Zinfandels have far fewer flavonoids. Whites once again came out short, as the bigger bolder more tannic wines seemed best for high flavonoid yields.

Resveratrol has been used in Traditional Chinese Medicine for centuries in the form of a plant called Polygonum cuspidatum for the treatment of liver and heart conditions. Why take a bitter herb when you can sip a fine wine?

According to recent statistics, year 2002 wine volume in the United States was approximately 595 million gallons. Up 34 million gallons of annual wine production when compared to 2001 records and the trend continues. California remains the largest wine producing state in the US with 90 percent coming from this state alone.

With wine sales in the United State reaching $21.1 billion in 2002, it has helped push the US to fourth in world wine production and third in consumption. The Greek philosopher Plato is quoted as saying Nothing more excellent or valuable than wine was ever granted by the gods to man. And this may be true beyond his imagination given the stated health benefits. The questions remains, with the increased consumption in recent years, will it have a noticeable impact on the health of Americans? Cheers.

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References: (upon request to author at jpsaleeby@aol.com)

JP Saleeby, MD is co-director of the Emergency Department at LRMC in Hinesville, GA. He is a strong advocate of nutritional medicine and an oneophile of sort founding the Savannah Wine Club. He holds faculty position at GSU in Statesboro, GA, lecturing graduate nurse practitioners. He also maintains a blog at http://www.docsaleeby.blogspot.com and http://www.members.aol.com/savannahwine. To email use jpsaleeby@aol.com.

Good news! A recent study suggested that resveratrol, a red wine compound, may extend our life.

The study was conducted on fries and worms to see if resveratrol can extend life in these creatures. Previous studies suggested that yeast life can be extended with resveratrol.

It was found that worms and fires fed resveratrol live 30% longer than those that were not fed resveratrol.

Fries and humans share many biological processes. Therefore, there is a chance this red wine compound may also extend life in humans.

Previous studies have found that resveratrol is protective against heart diseases largely due to the antioxidative properties of this compound.

However, the current finding, life-extension with resveratrol, may not be due to its antioxidative properties. Rather, resveratrol may act just like calorie-restriction that activates proteins called sirtuins similar to sir2. Sir2 is an important protein that is present in many animals and participate in the aging regulations.

More good news with resveratrol! Resveratrol does not have any negative impact on the fertility while calorie-restriction may cause infertility. Actually, resveratrol boosts the fertility of fries.

The researchers plan to continue their work on mice. If they can duplicate the same results in mice, resveratrol can be a wonder chemical that can help us extend our life to certain degree.

This study was done by David Sinclair of Harvard Medical School in Boston and colleagues at the University of Connecticut and Brown University in Rhode Island. The study was published in the July 13 issue of journal Nature.

About The Author

John Roberts is a freelance writer for foodconsumer.com

If you like the taste of a good brew, then here is some good news! In a recent research study of over 2,900 women and men, researchers found that beer, which contains silicon, may promote bone health. Silicon is a mineral that is thought to stimulate collagen production, which is a building block in bone formation. Wine is rich is phytochemicals, which may also benefit bones. Research does not show, however, in the battle of the sexes, that beer or wine has better or less results in either men or women. In a recent WebMD interview, Katherine Tucker, PhD says that it is possible that two glasses of wine could benefit men, while women may get a bone boost from two cans of beer. Another study of 2,847 people from the Framingham Osteoporosis Study found that men and pre-menopausal women who drank the most silicon, about 40 mg a day, had the highest bone mineral density, a measurement of bone health. Silicon is rarely listed on food labels, so it is hard to tell exactly how much you are consuming. But, you can estimate that one 12-ounce beer has approximately 7 mg of silicon.

It is important is that you drink any alcoholic beverage in moderation because while two cans of beer or two 6 ounce glasses of wine may be good for promoting bone growth, drinking more is harmful. The not-so-good news is that if you drink distilled beverages such as vodka or Scotch, daily consumption of these beverages has shown to actually promote osteoporosis. Osteoporosis is a bone-wasting disease that makes your bones brittle and more prone to breaks. The disease increases with age and is more common in women than men, especially postmenopausal women.

Drinking red wine has also shown to be linked to heart health. So, what we are seeing now is a diet that is good for the heart and another that is good for the bones. Because good nutrition is good for the heart, you can consider it good for the bones as well. Other studies have shown that good nutrition also plays a significant role in brain health.

So, how much beer or wine is good for your bones? Current recommendations are for two drinks a day for men and one drink a day for women. So, don’t jump and run to a keg party quite yet, remember that moderation is best.

Now, if you are not a beer or wine drinker, don’t start now just to promote bone growth. There are other ways to get silicon, and let us not forget that alcohol consumption raises other health risks such as osteoporosis itself. So, if you are interested in a healthier way to introduce silicon into your diet, you will want to eat dates, mangoes, melons, spinach, apples and even some bottled mineral waters will be good sources.

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Michele Webb owns her own website and is a member of a number of organizations for women Netpreneurs and business owners. She has over 20 years experience in health care, clinical trials, management, project management and software development. She currently lives in Las Vegas, Nevada USA with her two dogs.

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